SCHEMBL7314337

SCHEMBL7314337

O=C(O)C1CC1c1ccc(C2CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 6/20 0.54
HPGD P15428 1/20 0.47
HAO1 Q9UJM8 1/20 0.47
KMO O15229 1/20 0.47
ACMSD Q8TDX5 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
HRH3 Q9Y5N1 2/20 0.44
AKR1C3 P42330 1/20 0.43
AKR1C1 Q04828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7317863 0.98 FFAR1 (0.53) FFAR1HPGDHAO1KMOACMSD
SCHEMBL21624718 0.91 FFAR1 (0.59) FFAR1HPGDAKR1C3AKR1C1
SCHEMBL21624720 0.91 FFAR1 (0.59) FFAR1HPGDAKR1C3AKR1C1
SCHEMBL7317851 0.86 HDAC8 (0.46) HPGDHAO1KMOACMSDKDM4E
SCHEMBL1830698 0.80 ALDH1A1 (0.65) HPGDHAO1HDAC1HDAC8HDAC6
SCHEMBL1831403 0.80 SLC6A2 (0.56) HPGDHAO1HDAC1HDAC8HDAC6
SCHEMBL7312887 0.79 FFAR1 (0.44) FFAR1HPGDKMOACMSD
SCHEMBL11362941 0.78 HAO1 (0.51) HAO1KMOACMSDKDM4EGLA
SCHEMBL11362937 0.78 HAO1 (0.51) HAO1KMOACMSDKDM4EGLA
Hydrogen Peroxide SCHEMBL11391495 0.78 HAO1 (0.55) HAO1KMOACMSDKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed