Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314337 | 0.86 | FFAR1 (0.54) | HDAC8HDAC6HDAC1HPGDHAO1 | |
| Hydrochloric Acid SCHEMBL7317863 | 0.84 | FFAR1 (0.53) | HDAC8HDAC6HDAC1HPGDHAO1 | |
| SCHEMBL1831403 | 0.80 | SLC6A2 (0.56) | HDAC8HDAC6HDAC1HPGDHAO1 | |
| SCHEMBL1830698 | 0.80 | ALDH1A1 (0.65) | HDAC8HDAC6HDAC1HPGDHAO1 | |
| SCHEMBL7315840 | 0.80 | CEL (0.38) | ACMSDSIGMAR1SLC9A1KMO | |
| SCHEMBL7346168 | 0.79 | OPRL1 (0.38) | ACMSDSIGMAR1SLC9A1KMO | |
| SCHEMBL7319301 | 0.77 | HPGD (0.34) | HPGDACMSDSMN1; SMN2SIGMAR1HRH3 | |
| SCHEMBL10692330 | 0.77 | MAPT (0.46) | HAO1SMN1; SMN2 | |
| SCHEMBL24890441 | 0.76 | KDM1A (0.50) | HRH3SLC9A1 | |
| SCHEMBL21624718 | 0.76 | FFAR1 (0.59) | HPGDSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154483-C | Use of amines to produce drugs for preventing tumour cell proliferation | ��ŵ��-ʥ�������ɷ�����˾ | 2004-06-23 | — | — | CN | disclosed |
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |
| CN-1226825-A | Use of amines to produce drugs for preventing tumour cell proliferation | SANOFI SA (FR) | 1999-08-25 | — | — | CN | disclosed |