Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307507 | 0.98 | HTR2B (0.41) | HTR2BHPGDSIGMAR1MAPK1L3MBTL1 | |
| SCHEMBL7308947 | 0.95 | HTR2B (0.42) | HTR2BSIGMAR1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8858076 | 0.93 | MAPK1 (0.38) | HTR2BHPGDSIGMAR1MAPK1L3MBTL1 | |
| SCHEMBL7311554 | 0.92 | ACHE (0.41) | HTR2BALDH1A1 | |
| SCHEMBL8858099 | 0.92 | MAPK1 (0.38) | HTR2BHPGDSIGMAR1MAPK1L3MBTL1 | |
| SCHEMBL7309081 | 0.92 | ACHE (0.42) | HTR2BALDH1A1 | |
| SCHEMBL7317239 | 0.90 | HTR2B (0.42) | HTR2BSIGMAR1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7307194 | 0.90 | ACHE (0.42) | HTR2B | |
| SCHEMBL7314824 | 0.89 | LMNA (0.42) | HTR2BSIGMAR1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8858127 | 0.89 | HTR2B (0.37) | HTR2BSIGMAR1MAPK1L3MBTL1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |