Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858154 | 0.93 | LMNA (0.38) | LMNAHTR2BBCHEACHECACNA1F | |
| SCHEMBL7307194 | 0.93 | ACHE (0.42) | LMNAHTR2BBCHEACHECACNA1F | |
| SCHEMBL7304939 | 0.92 | HTR2B (0.42) | HTR2BBCHEACHECACNA1FCACNA1D | |
| SCHEMBL7309081 | 0.92 | ACHE (0.42) | LMNAHTR2BBCHEACHECACNA1F | |
| SCHEMBL7311554 | 0.91 | ACHE (0.41) | LMNAHTR2BBCHEACHECACNA1F | |
| SCHEMBL7308947 | 0.90 | HTR2B (0.42) | HTR2BALDH1A1SIGMAR1ITGB3ITGA2B | |
| SCHEMBL7307507 | 0.89 | HTR2B (0.41) | HTR2BALDH1A1SIGMAR1ITGB3ITGA2B | |
| SCHEMBL7315394 | 0.89 | HTR2B (0.41) | HTR2BALDH1A1SIGMAR1ITGB3ITGA2B | |
| SCHEMBL7308256 | 0.88 | ITGB3 (0.38) | LMNAHTR2BITGB3ITGA2B | |
| SCHEMBL8858108 | 0.87 | ACHE (0.39) | LMNAHTR2BBCHEACHECACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |