Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.41 |
| ▸ | BCHE | P06276 | 7/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309081 | 0.98 | ACHE (0.42) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7307194 | 0.95 | ACHE (0.42) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL8858106 | 0.94 | MAOA (0.38) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7315394 | 0.92 | HTR2B (0.41) | HTR2BALDH1A1 | |
| SCHEMBL8858168 | 0.92 | MAOA (0.38) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7314824 | 0.91 | LMNA (0.42) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL7307507 | 0.91 | HTR2B (0.41) | HTR2BALDH1A1 | |
| SCHEMBL7308947 | 0.89 | HTR2B (0.42) | HTR2BALDH1A1 | |
| SCHEMBL8858108 | 0.89 | ACHE (0.39) | ACHEBCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL8858076 | 0.86 | MAPK1 (0.38) | HTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |