Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316738 | 0.93 | GRIN1 (0.40) | GRIN1GRIN2BCHRM2CHRM1HTR7 | |
| SCHEMBL7318029 | 0.93 | GRIN1 (0.40) | GRIN1GRIN2BCHRM2CHRM1HTR7 | |
| SCHEMBL7316047 | 0.90 | GRIN1 (0.42) | GRIN1GRIN2BSIGMAR1CHRM2CHRM1 | |
| SCHEMBL7314486 | 0.89 | SIGMAR1 (0.35) | SIGMAR1CHRM2CHRM1HTR7TSHR | |
| SCHEMBL7313193 | 0.89 | SIGMAR1 (0.33) | SIGMAR1HTR7 | |
| SCHEMBL7307085 | 0.88 | SIGMAR1 (0.38) | SIGMAR1CHRM2CHRM1HTR7TSHR | |
| SCHEMBL7317112 | 0.88 | OPRL1 (0.38) | — | |
| SCHEMBL7343679 | 0.86 | OPRM1 (0.33) | SIGMAR1 | |
| SCHEMBL7317126 | 0.86 | GRIN1 (0.42) | GRIN1GRIN2BCHRM2CHRM1HTR7 | |
| SCHEMBL7314235 | 0.86 | GRIN1 (0.42) | GRIN1GRIN2BCHRM2CHRM1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |