Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316521 | 0.92 | SMN1; SMN2 (0.41) | HTR7KDM1ASMN1; SMN2BRD4CREBBP | |
| SCHEMBL7313690 | 0.91 | CYP1A2 (0.33) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL7304274 | 0.90 | SMN1; SMN2 (0.34) | HTR7OPRM1SMN1; SMN2BRD4 | |
| SCHEMBL7306204 | 0.89 | ITGB3 (0.38) | SIGMAR1HRH3HTR7KDM1ASMN1; SMN2 | |
| SCHEMBL7315401 | 0.89 | GRIN1 (0.41) | SIGMAR1HTR7 | |
| SCHEMBL7343679 | 0.87 | OPRM1 (0.33) | SIGMAR1OPRL1OPRM1 | |
| SCHEMBL7307085 | 0.85 | SIGMAR1 (0.38) | SIGMAR1HRH3HTR7OPRL1OPRM1 | |
| SCHEMBL7306902 | 0.84 | SMN1; SMN2 (0.40) | KDM1ASMN1; SMN2 | |
| SCHEMBL7314634 | 0.84 | GLA (0.38) | HRH3HTR7KDM1ATRPV6 | |
| SCHEMBL7314486 | 0.84 | SIGMAR1 (0.35) | SIGMAR1HRH3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |