Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343679 | 0.93 | OPRM1 (0.33) | SIGMAR1 | |
| SCHEMBL7307085 | 0.93 | SIGMAR1 (0.38) | SIGMAR1CHRM2CHRM1HTR7HRH3 | |
| SCHEMBL7308518 | 0.93 | CHRM2 (0.36) | CHRM2CHRM1GAAHTR7TSHR | |
| SCHEMBL7315016 | 0.92 | CHRM2 (0.38) | SIGMAR1CHRM2CHRM1GAAHTR7 | |
| SCHEMBL7305000 | 0.90 | CHRM2 (0.36) | SIGMAR1CHRM2CHRM1GAAHTR7 | |
| SCHEMBL7305758 | 0.90 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL7315401 | 0.89 | GRIN1 (0.41) | SIGMAR1CHRM2CHRM1HTR7TSHR | |
| SCHEMBL7309020 | 0.86 | CHRM2 (0.38) | CHRM2CHRM1HTR7TSHRHSD17B10 | |
| SCHEMBL7315805 | 0.86 | SMN1; SMN2 (0.35) | CHRM2CHRM1GAAHTR7TP53 | |
| SCHEMBL7309115 | 0.86 | HTR7 (0.38) | SIGMAR1CHRM2CHRM1HTR7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |