Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 9/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.71 |
| ▸ | GABRP | O00591 | 8/20 | 0.71 |
| ▸ | GABRD | O14764 | 8/20 | 0.71 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.71 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.71 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.71 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.71 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.71 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.71 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.71 |
| ▸ | GABRE | P78334 | 8/20 | 0.71 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.71 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.71 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.71 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.71 |
| ▸ | G6PD | P11413 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033067 | 1.00 | GABRA1 (0.71) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL3115466 | 1.00 | GABRA1 (0.71) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL19303484 | 0.89 | GABRA1 (0.61) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL22136186 | 0.89 | GABRP (0.56) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL29904078 | 0.87 | GABRA1 (0.82) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL22136187 | 0.87 | GABRP (0.55) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL29904117 | 0.87 | GABRA1 (0.82) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL29904068 | 0.85 | GABRA1 (0.88) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL26350407 | 0.85 | GABRA1 (0.88) | GABRA1GABRB2GABRPGABRDGABRB1 | |
| SCHEMBL17171297 | 0.84 | GABRA1 (0.78) | GABRA1GABRB2GABRPGABRDGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277838-B1 | ADMINISTERING DOSAGE OF ANXIOLYTIC AGENT TO ANIMAL | COCENSYS, INC. | 2001-08-21 | — | — | US | disclosed |
| US-6143736-A | USED TO ALLEVIATE STRESS, ANXIETY, SEIZURES, MOOD DISORDERS, PREMENSTRUAL SYNDROME(PMS) AND POSTNATAL DEPRESSION (PND AND TO INDUCE ANESTHESIA | COCENSYS, INC. (US) | 2000-11-07 | — | — | US | disclosed |
| WO-1998005337-A1 | USE OF GABA AND NMDA RECEPTOR LIGANDS FOR THE TREATMENT OF MIGRAINE HEADACHE | COCENSYS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |