Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 18/20 | 0.56 |
| ▸ | GABRD | O14764 | 18/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 18/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 18/20 | 0.56 |
| ▸ | GABRE | P78334 | 18/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115466 | 0.89 | GABRA1 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7315413 | 0.89 | GABRA1 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22033067 | 0.89 | GABRA1 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22136187 | 0.87 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22516226 | 0.83 | GABRA1 (0.81) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16190892 | 0.83 | GABRA1 (0.81) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19777258 | 0.83 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17792263 | 0.83 | GABRA1 (0.81) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17544857 | 0.82 | HSD11B1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10600842 | 0.82 | GABRD (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132504-A1 | 3.ALPHA.-HYDROXY-17.BETA.-AMIDE NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF | SAGE THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |