Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 12/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311493 | 0.97 | MAPK1 (0.45) | MAPK1L3MBTL1ACHE | |
| SCHEMBL7313926 | 0.94 | ACHE (0.51) | MAPK1L3MBTL1ACHE | |
| SCHEMBL7315671 | 0.88 | F10 (0.42) | — | |
| SCHEMBL7308886 | 0.88 | MAPK1 (0.49) | MAPK1L3MBTL1ACHE | |
| SCHEMBL7310668 | 0.88 | MAPK1 (0.49) | MAPK1L3MBTL1ACHE | |
| SCHEMBL7305380 | 0.86 | MAPK1 (0.46) | MAPK1L3MBTL1 | |
| SCHEMBL7313654 | 0.84 | MAPK1 (0.41) | MAPK1L3MBTL1ACHE | |
| SCHEMBL8858168 | 0.83 | MAOA (0.38) | MAPK1L3MBTL1ACHE | |
| SCHEMBL8858206 | 0.83 | MEN1 (0.42) | L3MBTL1 | |
| SCHEMBL8858106 | 0.81 | MAOA (0.38) | MAPK1L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |