Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | VNN1 | O95497 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268679 | 0.82 | MAPT (0.50) | LMNASRD5A2MAOBALDH1A1NR4A2 | |
| SCHEMBL423798 | 0.80 | DDR1 (0.59) | CES2LMNAVNN1SRD5A2MAOB | |
| SCHEMBL4268675 | 0.79 | RXFP1 (0.44) | ALDH1A1SMN1; SMN2NR4A2MEN1MAPT | |
| SCHEMBL27952195 | 0.77 | CES2 (0.56) | CES2LMNAVNN1SRD5A2MAOB | |
| SCHEMBL28882273 | 0.76 | CES2 (0.62) | CES2LMNASRD5A2MAOBKCNK3 | |
| SCHEMBL8035637 | 0.76 | L3MBTL1 (0.47) | LMNAALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6970291 | 0.75 | CES2 (0.61) | CES2LMNASRD5A2MAOBALDH1A1 | |
| SCHEMBL3092243 | 0.74 | EPHX1 (0.50) | LMNAMAOBALDH1A1NR4A2MEN1 | |
| SCHEMBL30758861 | 0.74 | CES2 (0.69) | CES2LMNASRD5A2KCNK3ALDH1A1 | |
| SCHEMBL423797 | 0.74 | MEN1 (0.62) | CES2LMNAVNN1SRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |