Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260612 | 0.86 | MAPT (0.48) | MAPTMEN1KMT2ARECQLNR4A2 | |
| SCHEMBL27704908 | 0.83 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1HDAC6 | |
| SCHEMBL7315604 | 0.82 | CES2 (0.50) | MAPTMEN1KMT2ANR4A2MAOB | |
| SCHEMBL4268675 | 0.82 | RXFP1 (0.44) | MAPTMEN1KMT2ANR4A2ACP3 | |
| SCHEMBL4262187 | 0.82 | MAPT (0.43) | MAPTMEN1KMT2ARECQLNR4A2 | |
| SCHEMBL13912551 | 0.78 | MAPT (0.40) | MAPTMEN1KMT2ARECQLNR4A2 | |
| SCHEMBL3092243 | 0.76 | EPHX1 (0.50) | MAPTMEN1KMT2ANR4A2MAOB | |
| SCHEMBL4263189 | 0.75 | MEN1 (0.49) | MAPTMEN1KMT2ARECQLNR4A2 | |
| SCHEMBL29010009 | 0.72 | ACP3 (0.54) | MAPTMEN1KMT2ANR4A2MLYCD | |
| SCHEMBL8035637 | 0.72 | L3MBTL1 (0.47) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC | 2009-03-26 | — | — | US | disclosed |
| US-7358364-B2 | treatment of diabetes and/or cancer; useful in the treatment of syndrome X; capable of inhibiting Protein tyrosine phosphatase | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| EP-1805159-A1 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006050212-A1 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20060094747-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, L.L.C. | 2006-05-04 | — | — | US | disclosed |
| US-20040266788-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266788-A1 | Substituted carboxylic acids | PTP4A1, PTPRS, G6PC1 | MAPT 1123/4885MEN1 2359/4885KMT2A 2771/4885 |
| US-20060094747-A1 | Substituted carboxylic acids | PTPRS, PTPRO, PTPRJ | MAPT 1249/4885MEN1 2928/4885KMT2A 2422/4885 |
| US-20090082392-A1 | Substituted Carboxylic Acids | PTPRJ, PTPRS, PTPRG | MAPT 1173/4885MEN1 3127/4885KMT2A 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.