Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 8/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322921 | 0.92 | BRS3 (0.49) | BRS3 | |
| SCHEMBL6534844 | 0.83 | BRS3 (0.46) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534773 | 0.82 | BRS3 (0.54) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534730 | 0.81 | BRS3 (0.52) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534662 | 0.78 | BRS3 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL9205903 | 0.73 | BRS3 (0.43) | BRS3AGTR1AGTR2 | |
| SCHEMBL8076004 | 0.72 | BRS3 (0.46) | BRS3AGTR1AGTR2 | |
| SCHEMBL73 | 0.71 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL6534713 | 0.69 | BRS3 (0.39) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534729 | 0.66 | BRS3 (0.57) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | claimed |