Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 9/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534773 | 0.89 | BRS3 (0.54) | BRS3AGTR1AGTR2 | |
| SCHEMBL8070880 | 0.84 | XDH (0.36) | BRS3AGTR1AGTR2 | |
| SCHEMBL8741233 | 0.81 | GCGR (0.32) | BRS3 | |
| SCHEMBL6534662 | 0.78 | BRS3 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL3460737 | 0.77 | PPARG (0.40) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534730 | 0.76 | BRS3 (0.52) | BRS3AGTR1AGTR2 | |
| SCHEMBL6534844 | 0.76 | BRS3 (0.46) | BRS3AGTR1AGTR2 | |
| SCHEMBL7050688 | 0.74 | AGTR1 (0.34) | BRS3AGTR1AGTR2 | |
| SCHEMBL7322921 | 0.73 | BRS3 (0.49) | BRS3 | |
| SCHEMBL7315650 | 0.72 | BRS3 (0.48) | BRS3AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019048-A1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | Merck Sharp Dohme (Italia) S.P.A. (IT) | 2000-07-19 | — | — | EP | claimed |
| WO-1999016437-A1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | MERCK SHARP DOHME (ITALIA) S.P.A. (IT) | 1999-04-08 | — | — | WO | claimed |