Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 6/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7311060 | 0.84 | ITGB3 (0.36) | — | |
| SCHEMBL7314657 | 0.76 | ITGB3 (0.48) | MASP2NAAAMAPTTP53CTSS | |
| SCHEMBL9568160 | 0.76 | YAP1 (0.41) | MASP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9568161 | 0.75 | BCHE (0.46) | MASP2 | |
| SCHEMBL7310281 | 0.71 | ITGB3 (0.47) | MASP2NAAAMAPTCTSLCTSS | |
| SCHEMBL7316413 | 0.71 | ITGB3 (0.47) | MASP2NAAAMAPTCTSLCTSS | |
| SCHEMBL7305795 | 0.71 | MASP2 (0.39) | MASP2CTSS | |
| SCHEMBL7305157 | 0.70 | MASP2 (0.37) | MASP2CTSLCTSS | |
| SCHEMBL7303107 | 0.70 | ITGB3 (0.46) | MASP2NAAAMAPTRAB9ACTSL | |
| SCHEMBL7311085 | 0.70 | MASP2 (0.37) | MASP2CTSLTP53CXCR3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |