Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 4/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310298 | 0.95 | HTR4 (0.32) | SMN1; SMN2GAADRD2DRD3CHRM2 | |
| SCHEMBL7308518 | 0.94 | CHRM2 (0.36) | SMN1; SMN2KDM4EALDH1A1GAAHTR7 | |
| SCHEMBL7343679 | 0.93 | OPRM1 (0.33) | — | |
| SCHEMBL7344820 | 0.90 | HRH1 (0.32) | GAAHTR7CHRM2CHRM1 | |
| SCHEMBL7315517 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53KDM4EALDH1A1NAAA | |
| SCHEMBL7315016 | 0.89 | CHRM2 (0.38) | GAAHTR7HSD17B10CHRM2CHRM1 | |
| SCHEMBL7309115 | 0.89 | HTR7 (0.38) | SMN1; SMN2KDM4EALDH1A1HTR7HSD17B10 | |
| SCHEMBL7316521 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53KDM4EALDH1A1HTR7 | |
| SCHEMBL7318029 | 0.88 | GRIN1 (0.40) | SMN1; SMN2KDM4EHTR7HSD17B10CHRM2 | |
| SCHEMBL7305674 | 0.87 | S1PR5 (0.33) | SMN1; SMN2GAADRD2DRD3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |