Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305674 | 0.95 | S1PR5 (0.33) | HRH1LTA4HCHRM2CHRM1GRIN1 | |
| SCHEMBL7314354 | 0.93 | CHRM2 (0.38) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7307155 | 0.91 | ITGB3 (0.34) | HRH1HTR7CHRM2CHRM1 | |
| SCHEMBL7315805 | 0.90 | SMN1; SMN2 (0.35) | HTR7CHRM2CHRM1GAA | |
| SCHEMBL7301320 | 0.89 | DRD2 (0.33) | LTA4HCHRM2CHRM1KDM1A | |
| SCHEMBL7305548 | 0.89 | CHRM2 (0.39) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7300978 | 0.88 | HTR7 (0.39) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7314634 | 0.88 | GLA (0.38) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7317126 | 0.87 | GRIN1 (0.42) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL7310298 | 0.87 | HTR4 (0.32) | HRH1CHRM2CHRM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |