Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | DRD3 | P35462 | 7/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.34 |
| ▸ | DRD4 | P21917 | 6/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301320 | 0.95 | DRD2 (0.33) | S1PR5NPY1RKDM1ADRD2DRD3 | |
| SCHEMBL7305548 | 0.90 | CHRM2 (0.39) | S1PR5NPY1RCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7319402 | 0.90 | SIGMAR1 (0.35) | NPY1RDRD2DRD3CHRM1CHRM2 | |
| SCHEMBL7305674 | 0.89 | S1PR5 (0.33) | S1PR5NPY1RKDM1ADRD2DRD3 | |
| SCHEMBL7311246 | 0.89 | DRD2 (0.35) | NPY1RKDM1ADRD2DRD3SMN1; SMN2 | |
| SCHEMBL7303867 | 0.87 | SMN1; SMN2 (0.38) | KDM1ACYP1A2MAPK1SMN1; SMN2CHRM1 | |
| SCHEMBL7307208 | 0.87 | LTA4H (0.49) | LTA4H | |
| SCHEMBL7315517 | 0.86 | SMN1; SMN2 (0.37) | KDM1ADRD2DRD3CYP1A2SMN1; SMN2 | |
| SCHEMBL7309143 | 0.85 | CYP1A2 (0.32) | S1PR5NPY1RKDM1ADRD2DRD3 | |
| SCHEMBL7314354 | 0.85 | CHRM2 (0.38) | CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |