Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.33 |
| ▸ | DRD3 | P35462 | 7/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.31 |
| ▸ | DRD4 | P21917 | 5/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315892 | 0.95 | S1PR5 (0.36) | DRD2DRD3LTA4HKDM1AS1PR5 | |
| SCHEMBL7319402 | 0.91 | SIGMAR1 (0.35) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL7314354 | 0.90 | CHRM2 (0.38) | CHRM2CHRM1 | |
| SCHEMBL7315517 | 0.89 | SMN1; SMN2 (0.37) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL7344820 | 0.89 | HRH1 (0.32) | LTA4HKDM1ACHRM2CHRM1 | |
| SCHEMBL7309705 | 0.87 | LTA4H (0.47) | LTA4HCHRM4ACHE | |
| SCHEMBL7311246 | 0.86 | DRD2 (0.35) | DRD2DRD3KDM1ACHRM2CHRM1 | |
| SCHEMBL7308005 | 0.86 | GLA (0.39) | KDM1AGLA | |
| SCHEMBL7305548 | 0.85 | CHRM2 (0.39) | S1PR5CHRM2CHRM1NPY1R | |
| SCHEMBL7305758 | 0.84 | SIGMAR1 (0.36) | DRD2DRD3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |