Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952839 | 0.76 | CYP1A2 (0.39) | PTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8544546 | 0.76 | CYP1A2 (0.39) | PTGER4ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28518576 | 0.76 | ERN1 (0.41) | LMNAALDH1A1HTT | |
| SCHEMBL29951110 | 0.76 | SRC (0.36) | LMNAPTGER4ALDH1A1HPGDKDM4E | |
| SCHEMBL23363158 | 0.67 | AGBL2 (0.35) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL335363 | 0.67 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL13947337 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL24764929 | 0.66 | KMT2A (0.54) | PTGER4ALDH1A1KDM4E | |
| SCHEMBL9131053 | 0.65 | ERN1 (0.36) | LMNACCR1CCR5CCR8 | |
| SCHEMBL28474138 | 0.65 | LMNA (0.34) | LMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111311-B1 | NON-RADIOACTIVE CARRIERS AND RADIOACTIVE DIAGNOSTIC AGENT | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0111311-A2 | Non-radioactive carriers and radioactive diagnostic agent | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1984-06-20 | — | — | EP | disclosed |
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4298739-A | ANTICOAGULANTS, ANTIINFLAMMATORY, ANTIULCER, VASODILATOR, PHOSPHODIESTERASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |
| US-3962038-A | FREEING, IRRADIATION POLYMERIZATION | DIRECTOR OF NATIONAL FOOD RESEARCH INSTITUTE (JA) | 1976-06-08 | — | — | US | disclosed |