SCHEMBL28474138

SCHEMBL28474138

O=Cc1cnc(C=O)c(C=O)c1C=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
CCR1 P32246 1/20 0.31
CCR5 P51681 1/20 0.31
CCR8 P51685 1/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5423975 0.70 CCR1 (0.48) LMNACCR1CCR5CCR8MEN1
SCHEMBL7315976 0.65 LMNA (0.33) LMNACCR1CCR5CCR8
SCHEMBL22296551 0.65 CCR1 (0.30) CCR1CCR5CCR8
SCHEMBL548457 0.64 TDP1 (0.50) LMNACCR1CCR5CCR8MEN1
SCHEMBL13348654 0.64 MEN1 (0.33) LMNAMEN1THRBBLMKMT2A
SCHEMBL8548155 0.64 ALDH1A1 (0.33) MEN1KMT2ATDP1
SCHEMBL28518576 0.64 ERN1 (0.41) LMNAKMT2ATRIM24TRIM33
SCHEMBL11804667 0.62 TDP1 (0.40) LMNAMEN1THRBBLMKMT2A
SCHEMBL9131053 0.62 ERN1 (0.36) LMNACCR1CCR5CCR8MEN1
SCHEMBL31489084 0.60 ERN1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909151-A Universal method for constructing chiral organic molecular cage 盐城工学院 2020-11-10 CN disclosed