Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914778 | 0.76 | MAOA (0.61) | MAOBMAOAEDNRABCHEACHE | |
| SCHEMBL16921617 | 0.74 | MAPK14 (0.44) | MAOBMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1483627 | 0.73 | PPARG (0.67) | MAOBEDNRABCHEACHEABCB1 | |
| SCHEMBL23258512 | 0.73 | TDP1 (0.52) | MAOBMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30558218 | 0.73 | MAOB (0.50) | MAOBMAOAPIN1 | |
| SCHEMBL27651725 | 0.71 | MEN1 (0.60) | MAOBMAOAEDNRABCHEACHE | |
| SCHEMBL752463 | 0.71 | EDNRA (0.69) | MAOBMAOAEDNRABCHEACHE | |
| SCHEMBL16921618 | 0.70 | LMNA (0.58) | MAOBMAOAACHEMAPTMAPK1 | |
| SCHEMBL7317979 | 0.70 | MAOB (0.49) | MAOBEDNRABCHEACHEMAPT | |
| SCHEMBL28199307 | 0.70 | BCHE (0.59) | MAOBMAOAEDNRABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |