Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 13/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323490 | 0.88 | PREP (0.46) | PREPF2 | |
| SCHEMBL7325825 | 0.85 | P2RX7 (0.40) | PREPF2 | |
| SCHEMBL7320008 | 0.85 | F2 (0.43) | PREPF2ALDH1A1CHRM2CHRM4 | |
| SCHEMBL7322848 | 0.84 | F2 (0.40) | PREPF2 | |
| SCHEMBL7331463 | 0.84 | F2 (0.40) | PREPF2CHRM2CHRM4CHRM1 | |
| SCHEMBL7324081 | 0.81 | F2 (0.42) | PREPF2ALDH1A1TSHR | |
| SCHEMBL7352616 | 0.81 | FAAH (0.37) | F2 | |
| SCHEMBL7322434 | 0.81 | PREP (0.48) | PREPCHRM2CHRM4CHRM1 | |
| SCHEMBL7354544 | 0.78 | PREP (0.51) | PREP | |
| SCHEMBL7322702 | 0.76 | PREP (0.40) | PREPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |