SCHEMBL7322848

SCHEMBL7322848

O=C[C@@H]1CCCN1C(=O)C1=CSC=CN1C(=O)C1CCc2ccccc2C1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.40
PREP P48147 13/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7331463 0.86 F2 (0.40) F2PREP
SCHEMBL7320008 0.85 F2 (0.43) F2PREP
SCHEMBL7324249 0.84 PREP (0.46) PREP
SCHEMBL7316140 0.84 PREP (0.45) F2PREP
SCHEMBL7324081 0.82 F2 (0.42) F2PREP
SCHEMBL7325825 0.80 P2RX7 (0.40) F2PREP
SCHEMBL7323490 0.78 PREP (0.46) F2PREP
SCHEMBL7352616 0.77 FAAH (0.37) F2
SCHEMBL7325883 0.76 PREP (0.49) PREP
SCHEMBL7441583 0.75 F2 (0.57) F2PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed