Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319093 | 1.00 | HDAC1 (0.53) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL7316237 | 1.00 | HDAC1 (0.53) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL9542310 | 0.92 | NPC1 (0.56) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL9790512 | 0.92 | NPC1 (0.56) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL7315952 | 0.90 | HDAC1 (0.67) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL7322092 | 0.90 | HDAC1 (0.67) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL7315942 | 0.90 | HDAC1 (0.67) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL9790518 | 0.88 | LMNA (0.59) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL9790446 | 0.88 | LMNA (0.56) | HDAC1MAOBALDH1A1LMNAHPGD | |
| SCHEMBL9790510 | 0.88 | RAB9A (0.51) | HDAC1MAOBALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901465-B1 | COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE ACTIVITIES | ITALFARMACO SPA (IT) | 2000-09-27 | — | — | EP | disclosed |
| US-6034096-A | Compounds with anti-inflammatory and immunosuppressive activities | ITALFARMACO S.P.A. (IT) | 2000-03-07 | — | — | US | disclosed |
| EP-0901465-A1 | COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE ACTIVITIES | ITALFARMACO S.p.A. (IT) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043251-A1 | COMPOUNDS WITH ANTI-INFLAMMATORY AND IMMUNOSUPPRESSIVE ACTIVITIES | ITALFARMACO S.P.A. (IT) | 1997-11-20 | — | — | WO | disclosed |