Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321851 | 0.89 | METAP2 (0.58) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7318557 | 0.89 | ACLY (0.54) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7313454 | 0.87 | ACLY (0.51) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7325273 | 0.86 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7317804 | 0.86 | KMT2A (0.54) | MEN1KMT2AALDH1A1FABP4SMN1; SMN2 | |
| SCHEMBL7351226 | 0.85 | MEN1 (0.48) | MEN1KMT2AALDH1A1FABP4MCL1 | |
| SCHEMBL7322650 | 0.83 | METAP2 (0.58) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7322098 | 0.83 | MTNR1A (0.48) | MEN1KMT2AFABP4HTTSMN1; SMN2 | |
| SCHEMBL7325047 | 0.83 | KMT2A (0.46) | MEN1KMT2AALDH1A1FABP4HTT | |
| SCHEMBL7315132 | 0.82 | MEN1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |