SCHEMBL731627

SCHEMBL731627

CO[Si](C)(CC(C)CCl)OC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4191771 0.84
SCHEMBL17668984 0.81
SCHEMBL732311 0.80 MAPK1 (0.32) MAPK1
SCHEMBL17669005 0.78
SCHEMBL320162 0.77 MAPK1 (0.33) MAPK1
SCHEMBL9704170 0.77
SCHEMBL734468 0.76
SCHEMBL17668923 0.76 LMNA (0.30)
SCHEMBL3246466 0.75 MAPK1 (0.32) MAPK1
SCHEMBL375875 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552187-A Method for synthesizing 2-methyl-3-mercaptopropyl alkoxy silane by thiourea method 湖北康和园新材料有限公司 2025-03-04 CN claimed
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US claimed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US claimed
EP-1476450-B1 METHOD OF MAKING N-2-AMINOETHYL AMINOALKYLALKOXYSILANES WITH ETHYLENE DIAMINE SALT RECYCLE DOW CORNING (US) 2010-03-03 EP claimed
CN-1267440-C Method for preparing N- [ 2-aminoethyl ] aminoalkyl alkoxy silane by using ethylene diamine salt circulation process DOW CORNING (US) 2006-08-02 CN claimed
EP-1004587-B1 3-Methacryloxyisobutylalkoxysilanes and 3-acryloxyisobutylalkoxysilanes DEGUSSA (DE) 2004-07-14 EP claimed
US-6608225-B1 Esterification of alkali metal acrylate with a 3-chloroiso-butylalkoxysilane; adhesion promoters, protective coatings DEGUSSA AG (DE) 2003-08-19 US claimed
EP-1004587-A2 3-Methacryloxyisobutylalkoxysilanes and 3-acryloxyisobutylalkoxysilanes Degussa-Hüls Aktiengesellschaft (DE) 2000-05-31 EP claimed
CN-119552187-A Method for synthesizing 2-methyl-3-mercaptopropyl alkoxy silane by thiourea method 湖北康和园新材料有限公司 2025-03-04 CN disclosed
EP-2906569-B1 HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES USING PEROXIDE PROMOTERS MOMENTIVE PERFORMANCE MAT INC (US) 2018-06-13 EP disclosed
EP-3009439-B1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHINETSU CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-9556208-B2 Hydrosilylation synthesis of haloalkylorganosilanes using peroxide promoters MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-01-31 US disclosed
US-9371341-B2 Cyclic aminoorganoxysilane compound and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-21 US disclosed
EP-3009439-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2016-04-20 EP disclosed
US-5162560-A Chemical intermediates DOW CORNING CORPORATION (US) 1992-11-10 US disclosed
EP-0499407-A1 Crosslinkers and chain extenders for room temperature vulcanization or crosslinking of polymers DOW CORNING CORPORATION (US) 1992-08-19 EP disclosed
EP-0499409-A1 Olefinic and acetylenic azasilacyclopentanes DOW CORNING CORPORATION (US) 1992-08-19 EP disclosed
US-5136064-A Reacting organosilicon compound with grignard reagent in presence of ether, then acetyl chloride and lewis acid and amine DOW CORNING CORPORATION (US) 1992-08-04 US disclosed
US-5110967-A No evolution of volatile by-products; sealants DOW CORNING CORPORATION (US) 1992-05-05 US disclosed
US-4645844-A Functionally substituted phenoxyalkyl alkoxysilanes and method for preparing same M&T CHEMICALS INC. (US) 1987-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217026-A1 Method for producing organosilanes TST, STS, HAO2 MAPK1 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.