SCHEMBL732311

SCHEMBL732311

CO[Si](C)(C)CC(C)CCl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8751638 0.82 MAPK1 (0.33) MAPK1
SCHEMBL17668934 0.81
SCHEMBL731627 0.80 MAPK1 (0.32) MAPK1
SCHEMBL17669055 0.78
SCHEMBL320162 0.77 MAPK1 (0.33) MAPK1
SCHEMBL734170 0.76
SCHEMBL17669130 0.76 LMNA (0.30)
SCHEMBL3246466 0.75 MAPK1 (0.32) MAPK1
SCHEMBL374920 0.75
SCHEMBL2548651 0.75 GABBR2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN claimed
CN-119552187-A Method for synthesizing 2-methyl-3-mercaptopropyl alkoxy silane by thiourea method 湖北康和园新材料有限公司 2025-03-04 CN claimed
US-8138365-B2 Method for producing organosilanes EVONIK DEGUSSA GMBH (DE) 2012-03-20 US claimed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US claimed
EP-4590737-B1 COMPOSITION AND ARTICLE INCLUDING A THERMOPLASTIC AND A BRANCHED SILSESQUIOXANE POLYMER AND RELATED PROCESS 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-29 EP disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
EP-4590737-A1 COMPOSITION AND ARTICLE INCLUDING A THERMOPLASTIC AND A BRANCHED SILSESQUIOXANE POLYMER AND RELATED PROCESS 3M Innovative Properties Company (US) 2025-07-30 EP disclosed
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN disclosed
CN-119552187-A Method for synthesizing 2-methyl-3-mercaptopropyl alkoxy silane by thiourea method 湖北康和园新材料有限公司 2025-03-04 CN disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
WO-2024127135-A2 METHODS FOR SILANIZATION OF SUBSTRATES MEDTRONIC, INC. (US) 2024-06-20 WO disclosed
WO-2024062392-A1 COMPOSITION AND ARTICLE INCLUDING A THERMOPLASTIC AND A BRANCHED SILSESQUIOXANE POLYMER AND RELATED PROCESS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-03-28 WO disclosed
US-20100217026-A1 Method for producing organosilanes EVONIK OPERATIONS GMBH (DE) 2010-08-26 US disclosed
EP-1925627-B1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHINETSU CHEMICAL CO (JP) 2010-04-28 EP disclosed
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2009-02-26 US disclosed
EP-1919929-A4 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS INC (US) 2008-08-06 EP disclosed
US-20080132652-A1 WATER-SOLUBLE SILICON-CONTAINING POLYMER, MAKING METHOD, COATING COMPOSITION, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-06-05 US disclosed
EP-1925627-A1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2008-05-28 EP disclosed
EP-1919929-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND Pharmaceuticals, Inc. (US) 2008-05-14 EP disclosed
WO-2007019221-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217026-A1 Method for producing organosilanes TST, STS, HAO2 MAPK1 4421/4885
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS SI, SLC29A2, SLC29A1 MAPK1 3053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.