Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319236 | 0.90 | RAB9A (0.40) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7321020 | 0.89 | RAB9A (0.45) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7318536 | 0.87 | SMN1; SMN2 (0.46) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10584472 | 0.86 | SLC6A2 (0.39) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7316423 | 0.86 | ALDH1A1 (0.43) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7318664 | 0.81 | CNR2 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7370142 | 0.77 | NR4A2 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7323963 | 0.77 | GAA (0.46) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7375083 | 0.70 | TDP1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL7316351 | 0.70 | NPC1 (0.55) | NPC1RAB9AKMT2ACDK4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |