Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318664 | 0.93 | CNR2 (0.41) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL7317190 | 0.93 | LTB4R2 (0.40) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL7316348 | 0.86 | NPC1 (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7366401 | 0.78 | HDAC1 (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7313154 | 0.77 | ALDH1A1 (0.43) | ALDH1A1NPC1GLAHTTRAB9A | |
| SCHEMBL7323963 | 0.76 | GAA (0.46) | ALDH1A1NPC1HTTRAB9AMEN1 | |
| SCHEMBL7372051 | 0.76 | HDAC1 (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7321020 | 0.75 | RAB9A (0.45) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7318502 | 0.74 | SLC6A2 (0.39) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL7376615 | 0.73 | EPHX2 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |