Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319236 | 0.89 | RAB9A (0.40) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7321020 | 0.88 | RAB9A (0.45) | SMN1; SMN2ALDH1A1HTTKMT2ANPC1 | |
| SCHEMBL7316348 | 0.87 | NPC1 (0.53) | SMN1; SMN2ALDH1A1MAPK1KMT2ANPC1 | |
| SCHEMBL10584472 | 0.85 | SLC6A2 (0.39) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7321818 | 0.80 | KMT2A (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7316423 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7318543 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HTTACHEBCHE | |
| SCHEMBL7375083 | 0.70 | TDP1 (0.39) | ALDH1A1ACHEBCHETDP1MEN1 | |
| SCHEMBL19002580 | 0.69 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1HTTACHEBCHE | |
| SCHEMBL7267087 | 0.69 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1HTTACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |