Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 9/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316389 | 1.00 | F2 (0.39) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7020342 | 0.82 | F2 (0.40) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7140320 | 0.81 | F2 (0.47) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7675994 | 0.80 | F2 (0.42) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7316380 | 0.80 | F2 (0.42) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL3247707 | 0.78 | F2 (0.60) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL3240576 | 0.78 | MEN1 (0.44) | PLAUKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7316378 | 0.77 | TPSAB1 (0.44) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL7912621 | 0.76 | TPSAB1 (0.61) | F2F7F3PRSS1TPSAB1 | |
| SCHEMBL3247710 | 0.76 | P2RX7 (0.43) | F2F7F3PRSS1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |