Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247707 | 0.82 | F2 (0.60) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7140320 | 0.81 | F2 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7403728 | 0.80 | TPSAB1 (0.49) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7316380 | 0.80 | F2 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7675994 | 0.80 | F2 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL5885589 | 0.79 | F2 (0.59) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021593 | 0.78 | TPSAB1 (0.53) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL8205180 | 0.78 | TPSAB1 (0.52) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7912621 | 0.78 | TPSAB1 (0.61) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020342 | 0.78 | F2 (0.40) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |