Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309897 | 0.79 | TBXA2R (0.41) | TSHRMAPTPPARGPPARAHDAC11 | |
| SCHEMBL7314358 | 0.75 | TSHR (0.45) | TSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL7314215 | 0.74 | SMN1; SMN2 (0.34) | TSHRPMP22ALDH1A1TDP1MEN1 | |
| SCHEMBL11401848 | 0.65 | LMNA (0.46) | LMNATSHRNFKB1PMP22ABCC4 | |
| SCHEMBL28879499 | 0.65 | TSHR (0.50) | LMNATSHRNFKB1PMP22ABCC4 | |
| SCHEMBL13213692 | 0.65 | TSHR (0.44) | LMNATSHRNFKB1PMP22ABCC4 | |
| SCHEMBL3623997 | 0.65 | LMNA (0.41) | LMNATSHRNFKB1PMP22AKR1B1 | |
| SCHEMBL3624000 | 0.65 | LMNA (0.41) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL28253795 | 0.64 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL18227972 | 0.64 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |