Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 2/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316562 | 0.88 | CA12 (0.39) | ALDH1A1HSD11B1MAPTSMN1; SMN2TSHR | |
| SCHEMBL7314215 | 0.83 | SMN1; SMN2 (0.34) | TBXA2RALDH1A1TBXAS1SMN1; SMN2CYP1A2 | |
| SCHEMBL7314358 | 0.82 | TSHR (0.45) | ALDH1A1MAPTCTSSCTSKSMN1; SMN2 | |
| SCHEMBL7316601 | 0.79 | LMNA (0.34) | ALDH1A1HDAC11MAPTTSHRPPARG | |
| SCHEMBL7314859 | 0.74 | TBXA2R (0.35) | TBXA2RALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7306091 | 0.73 | EBP (0.54) | TBXA2RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7304642 | 0.73 | EBP (0.54) | TBXA2RHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7315392 | 0.72 | BLM (0.41) | TBXA2RALDH1A1TBXAS1SMN1; SMN2CYP1A2 | |
| SCHEMBL7316961 | 0.72 | ALDH1A1 (0.38) | TBXA2RALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7314866 | 0.68 | CES2 (0.35) | TBXA2RALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |