Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309897 | 0.82 | TBXA2R (0.41) | TSHRALDH1A1CTSSCTSKSMN1; SMN2 | |
| SCHEMBL7314215 | 0.76 | SMN1; SMN2 (0.34) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7315826 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7316601 | 0.75 | LMNA (0.34) | TSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL7302669 | 0.74 | HPGD (0.42) | TSHRHPGDALDH1A1CTSSCTSK | |
| SCHEMBL7314859 | 0.68 | TBXA2R (0.35) | TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5226414 | 0.67 | CTSC (0.36) | TSHRHPGDALDH1A1CTSSCTSK | |
| SCHEMBL14432518 | 0.67 | CTSC (0.36) | TSHRHPGDALDH1A1CTSSCTSK | |
| SCHEMBL7304642 | 0.66 | EBP (0.54) | TSHRSMN1; SMN2MAPT | |
| SCHEMBL7306091 | 0.66 | EBP (0.54) | TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |