Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1205400 | 0.90 | TSHR (0.66) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL1188279 | 0.88 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL1929760 | 0.86 | TUBB4A (0.47) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL2390640 | 0.85 | GSK3B (0.52) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL11162299 | 0.85 | PKM (0.60) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL12418371 | 0.85 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4EGSK3B | |
| SCHEMBL7369355 | 0.84 | HPGD (0.46) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL1447632 | 0.84 | TPMT (0.51) | MEN1KMT2AALDH1A1KDM4EGSK3B | |
| SCHEMBL7046987 | 0.84 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL9828028 | 0.84 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341831-B | 7H- [1,2,4] triazolo [3,4-b ] [1,3,4] thiadiazine-phenylhydrazone type compounds | 贵州医科大学 | 2020-10-09 | — | — | CN | claimed |
| US-12421257-B2 | Compositions and methods for inhibiting group II intron RNA | YALE UNIVERSITY (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240018169-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA | UNIV YALE (US) | 2024-01-18 | — | — | US | disclosed |
| US-11739104-B2 | Compositions and methods for inhibiting group II intron RNA | YALE UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| EP-4219486-A1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | Temple University of the Commonwealth System of Higher Education (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219486-A1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | Temple University of the Commonwealth System of Higher Education (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3571196-B1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | UNIV TEMPLE (US) | 2023-01-04 | — | — | EP | disclosed |
| EP-3571196-B1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | UNIV TEMPLE (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20220024912-A1 | COMPOUNDS FOR TREATMENT OF CANCER | Oncternal Therapeutics, Inc. (US) | 2022-01-27 | — | — | US | disclosed |
| US-11084811-B2 | Compounds for treatment of cancer | Oncternal Therapeutics, Inc. (US) | 2021-08-10 | — | — | US | disclosed |
| US-4469695-A | 2-(4-Hydroxyalkyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives | AYERST, MCKENNA & HARRISON, INC. (CA) | 1984-09-04 | — | — | US | disclosed |
| US-4451650-A | ANTITUMOR AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0107130-A1 | Pyrido(4,3-b)(1,4) oxazines and pyrido(4,3-b) (1,4)thiazines | Southern Research Institute (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4446141-A | Hypotensive piperidine derivatives | KYOWA HAKKO KOGYO CO. (JP) | 1984-05-01 | — | — | US | disclosed |
| EP-0018417-B1 | NOVEL PIPERIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1982-06-30 | — | — | EP | disclosed |
| EP-0034894-A2 | 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives, processes for their preparation, intermediates used in the processes and the preparation thereof and pharmaceutical compositions containing the derivatives | AYERST, MCKENNA AND HARRISON INC. (CA) | 1981-09-02 | — | — | EP | disclosed |
| EP-0018417-A1 | Novel piperidine derivatives and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1980-11-12 | — | — | EP | disclosed |
| US-4190594-A | ABSORBERS OF ULTRAVIOLET RADIATION | JOHNSON & JOHNSON (US) | 1980-02-26 | — | — | US | disclosed |
| US-4108880-A | ULTRAVIOLET ABSORBERS | JOHNSON & JOHNSON (US) | 1978-08-22 | — | — | US | disclosed |
| US-3997557-A | ANTIARRHYTHMIA, CNS DEPRESSANT, ANTIINFLAMMATORY, HYPOTENSIVE | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421257-B2 | Compositions and methods for inhibiting group II intron RNA | NSUN2, RBM22, RNGTT | MEN1 3207/4885KMT2A 2712/4885ALDH1A1 2984/4885 |
| US-11739104-B2 | Compositions and methods for inhibiting group II intron RNA | NSUN2, RBM22, RNGTT | MEN1 3207/4885KMT2A 2712/4885ALDH1A1 2984/4885 |
| US-20240018169-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA | NSUN2, RBM22, RNGTT | MEN1 3207/4885KMT2A 2712/4885ALDH1A1 2984/4885 |
| US-11084811-B2 | Compounds for treatment of cancer | KLK3, BRDT, ACP3 | MEN1 165/4885KMT2A 2242/4885ALDH1A1 209/4885 |
| US-20220024912-A1 | COMPOUNDS FOR TREATMENT OF CANCER | KLK3, BRDT, ACP3 | MEN1 165/4885KMT2A 2242/4885ALDH1A1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.