Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.42 |
| ▸ | ACHE | P22303 | 8/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617782 | 0.88 | ALDH1A1 (0.58) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL7317654 | 0.80 | ACHE (0.42) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL7301316 | 0.79 | MAOB (0.59) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL9136983 | 0.76 | MAOB (0.39) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL7307720 | 0.74 | RAB9A (0.39) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL7312144 | 0.71 | MAOB (0.47) | MAOBACHEMAOA | |
| SCHEMBL7301295 | 0.71 | ACHE (0.62) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL7304194 | 0.71 | MAOB (0.78) | ALDH1A1HPGDMAOBACHE | |
| SCHEMBL7296704 | 0.71 | MAOB (0.55) | ALDH1A1POLBHSP90AA1HPGDTSHR | |
| SCHEMBL7294118 | 0.70 | ALDH1A1 (0.57) | ALDH1A1POLBHSP90AA1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |