Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617544 | 0.90 | ACHE (0.49) | RAB9AMAOBACHEKCNH2MAOA | |
| SCHEMBL7294324 | 0.83 | MAOB (0.51) | RAB9AMAOBACHEMAOAALDH1A1 | |
| SCHEMBL7303830 | 0.79 | ACHE (0.55) | RAB9AMAOBACHEMAOAALDH1A1 | |
| SCHEMBL9135893 | 0.79 | RAB9A (0.39) | RAB9ANPC1GAAKMT2A | |
| SCHEMBL5617681 | 0.77 | MAOB (0.53) | RAB9AMAOBACHEMAOAALDH1A1 | |
| SCHEMBL7295636 | 0.77 | MAOB (0.53) | RAB9AMAOBACHEMAOAALDH1A1 | |
| SCHEMBL7317654 | 0.77 | ACHE (0.42) | RAB9ANPC1KMT2AMAOBACHE | |
| SCHEMBL5618127 | 0.77 | MAOB (0.52) | RAB9AMAOBACHEMAOAALDH1A1 | |
| SCHEMBL7316699 | 0.74 | ALDH1A1 (0.44) | RAB9AMAOBACHEMAOAALDH1A1 | |
| SCHEMBL7308829 | 0.69 | MAOB (0.53) | MAOBACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |