Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.67 |
| ▸ | KDM1A | O60341 | 1/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 10/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393314 | 0.94 | CYP1B1 (0.67) | CYP1B1CYP1A2CYP1A1KDM1AABCC1 | |
| SCHEMBL10472448 | 0.93 | CYP1A2 (0.63) | CYP1B1CYP1A2CYP1A1KDM1AABCC1 | |
| SCHEMBL8429540 | 0.90 | EGFR (0.59) | CYP1B1CYP1A2KDM4EALDH1A1POLB | |
| SCHEMBL24183777 | 0.88 | KDM4E (0.69) | CYP1A2XDHIP6K2KDM4EALDH1A1 | |
| SCHEMBL8429585 | 0.88 | CYP1B1 (0.56) | CYP1B1CYP1A2CYP1A1ABCC1KDM4E | |
| SCHEMBL10473384 | 0.87 | CYP1B1 (0.72) | CYP1B1CYP1A2CYP1A1KDM1AABCC1 | |
| SCHEMBL8431160 | 0.87 | ALDH1A1 (0.56) | CYP1B1CYP1A2CYP1A1ABCC1KDM4E | |
| SCHEMBL7306885 | 0.86 | CYP1B1 (0.54) | CYP1B1CYP1A2CYP1A1KDM1AABCC1 | |
| SCHEMBL4397722 | 0.86 | KDM4E (0.70) | CYP1B1CYP1A2CYP1A1HDAC6KDM4E | |
| SCHEMBL8427276 | 0.86 | CYP1B1 (0.56) | CYP1B1CYP1A2CYP1A1KDM1AABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |