Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP10 | P09238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117923 | 0.84 | DRD2 (0.51) | DRD3OPRM1TSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL5356989 | 0.84 | OPRM1 (0.57) | OPRM1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4432360 | 0.83 | DRD2 (0.50) | DRD3OPRM1TSHRSMN1; SMN2HSD11B1 | |
| Hydrochloric Acid SCHEMBL7624556 | 0.83 | OPRM1 (0.56) | OPRM1TSHRSMN1; SMN2 | |
| SCHEMBL28231788 | 0.82 | OPRM1 (0.43) | OPRM1HSD11B1DPP4MMP3MMP10 | |
| SCHEMBL7317535 | 0.81 | DRD3 (0.47) | DRD3OPRM1TSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL378896 | 0.80 | APP (0.50) | OPRM1HSD11B1 | |
| Hydrochloric Acid SCHEMBL5916170 | 0.79 | APP (0.49) | OPRM1HSD11B1 | |
| SCHEMBL31368038 | 0.78 | OPRM1 (0.51) | OPRM1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8353580 | 0.78 | HSD11B1 (0.46) | OPRM1HSD11B1DPP4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |