Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313197 | 0.87 | THRA (0.36) | THRATHRBESR1L3MBTL1FFAR1 | |
| SCHEMBL7315821 | 0.85 | THRA (0.35) | THRATHRBESR1FFAR1FFAR4 | |
| SCHEMBL7320207 | 0.76 | THRA (0.37) | THRATHRBESR1FFAR1FFAR4 | |
| SCHEMBL7309552 | 0.75 | THRA (0.41) | THRATHRBESR1PDE6DL3MBTL1 | |
| SCHEMBL7316157 | 0.73 | PDE3B (0.40) | ALDH1A1KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL7320201 | 0.73 | THRA (0.36) | THRATHRBESR1PDE6DFFAR1 | |
| SCHEMBL7319377 | 0.71 | PDE6D (0.33) | PDE6DALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7308962 | 0.70 | HPGD (0.42) | THRATHRBALDH1A1CYP3A4MAPT | |
| SCHEMBL7316914 | 0.69 | THRA (0.46) | THRATHRBL3MBTL1BCHEACHE | |
| SCHEMBL7310719 | 0.67 | THRA (0.42) | THRATHRBESR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |