Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310929 | 0.84 | RAB9A (0.43) | HPGDTSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7311442 | 0.83 | NPC1 (0.43) | HPGDTSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7319069 | 0.77 | ALDH1A1 (0.43) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7309552 | 0.76 | THRA (0.41) | HPGDTSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7316914 | 0.72 | THRA (0.46) | THRATHRBCYSLTR2CYSLTR1LMNA | |
| SCHEMBL7317566 | 0.70 | THRB (0.44) | HPGDTSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7317826 | 0.70 | THRA (0.35) | HPGDTSHRSMN1; SMN2THRATHRB | |
| SCHEMBL7306686 | 0.70 | THRA (0.36) | TSHRSMN1; SMN2THRATHRBCYSLTR2 | |
| SCHEMBL16175317 | 0.69 | MAPT (0.46) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9117309 | 0.68 | HPGD (0.65) | HPGDTSHRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |