Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE6D | O43924 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310719 | 0.84 | THRA (0.42) | THRATHRBMAPTALDH1A1ESR1 | |
| SCHEMBL7311177 | 0.83 | THRA (0.42) | THRATHRBMAPTALDH1A1ESR1 | |
| SCHEMBL7308962 | 0.76 | HPGD (0.42) | THRATHRBMAPTALDH1A1NPC1 | |
| SCHEMBL7317826 | 0.75 | THRA (0.35) | THRATHRBMAPTALDH1A1PDE6D | |
| SCHEMBL7316914 | 0.72 | THRA (0.46) | THRATHRBMAPTALDH1A1CYP1A2 | |
| SCHEMBL7317566 | 0.69 | THRB (0.44) | THRATHRBMAPTALDH1A1NPC1 | |
| SCHEMBL7318364 | 0.69 | THRA (0.39) | THRATHRBMAPTALDH1A1NPC1 | |
| SCHEMBL10376795 | 0.69 | SIRT5 (0.44) | THRATHRBMAPTALDH1A1HPGD | |
| SCHEMBL7344986 | 0.69 | LMNA (0.48) | THRATHRBALDH1A1NPC1TSHR | |
| SCHEMBL10374480 | 0.68 | SIRT5 (0.43) | THRATHRBMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |