Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902801 | 0.87 | L3MBTL1 (0.51) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL8329550 | 0.83 | L3MBTL1 (0.54) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL21626263 | 0.83 | ALDH1A1 (0.50) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL29029181 | 0.83 | ALDH1A1 (0.50) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL25311343 | 0.82 | LMNA (0.47) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL5491275 | 0.82 | SLC1A3 (0.57) | KMT2ASLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL8329553 | 0.81 | L3MBTL1 (0.51) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL1859515 | 0.81 | SMN1; SMN2 (0.46) | L3MBTL1LMNAALDH1A1MMP8PPARG | |
| SCHEMBL7740325 | 0.81 | SLC1A3 (0.50) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 | |
| SCHEMBL16370074 | 0.81 | LMNA (0.46) | L3MBTL1LMNAKMT2ASLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389610-A | For cardiovascular disorders | SCHERING CORPORATION (US) | 1995-02-14 | — | — | US | disclosed |
| EP-0502075-A1 | CARBOXYALKYLCARBONYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007386-A1 | CARBOXYALKYLCARBONYL AMINOACID ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-05-30 | — | — | WO | disclosed |