Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317868 | 0.88 | PARP10 (0.57) | SGMS2ALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL1388095 | 0.86 | FAAH (0.60) | SGMS2ALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL29055574 | 0.84 | FAAH (0.57) | SGMS2ALDH1A1MEN1KMT2APARP10 | |
| SCHEMBL7907804 | 0.83 | PARP10 (0.54) | SGMS2MEN1KMT2APARP10PARP15 | |
| SCHEMBL7322027 | 0.81 | PARP10 (0.46) | ALDH1A1PARP10PARP15SIRT2PARP2 | |
| SCHEMBL5839516 | 0.81 | NR4A1 (0.63) | SGMS2ALDH1A1PARP10PTGER1FOLH1 | |
| SCHEMBL3064765 | 0.81 | FAAH (0.54) | ALDH1A1MEN1KMT2APARP10PARP15 | |
| SCHEMBL7316318 | 0.81 | SGMS2 (0.54) | SGMS2ALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL933677 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KMT2AFAAHCNR1CNR2 | |
| SCHEMBL8038285 | 0.77 | MAPK8 (0.49) | ALDH1A1MEN1KMT2APARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872138-A | INHIBITING LOSS OF BLOOD PLATELETS, INHIBITING FORMATION OF BLOOD PLATELET AGGREGATES, INHIBITING FORMATION OF FIBRIN, INHIBITING THROMBUS FORMATION, AND INHIBITING EMBOLUS FORMATION IN A MAMMAL | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |