Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312450 | 0.89 | LMNA (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7308459 | 0.85 | THRA (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7319873 | 0.84 | THRA (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7313188 | 0.81 | LMNA (0.52) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7315762 | 0.81 | LMNA (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL26369296 | 0.79 | TSHR (0.49) | LMNAL3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7310331 | 0.77 | PKM (0.43) | THRBLMNASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7320757 | 0.76 | LMNA (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7315787 | 0.76 | LMNA (0.46) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7307893 | 0.75 | LMNA (0.43) | THRATHRBLMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |