Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309041 | 0.88 | LMNA (0.43) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7308459 | 0.86 | THRA (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7318314 | 0.84 | THRA (0.43) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL10374771 | 0.83 | LMNA (0.47) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL10377100 | 0.83 | LMNA (0.47) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7321047 | 0.83 | ALDH1A1 (0.47) | THRATHRBALOX15HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL7318415 | 0.82 | ALDH1A1 (0.46) | THRATHRBALOX15HSD17B10TSHR | |
| SCHEMBL27118714 | 0.81 | ALDH1A1 (0.47) | THRATHRBLMNASMN1; SMN2ALOX15 | |
| SCHEMBL7309433 | 0.80 | ALDH1A1 (0.44) | THRATHRBLMNASMN1; SMN2NPSR1 | |
| SCHEMBL7318409 | 0.80 | ALDH1A1 (0.46) | THRATHRBLMNASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |