Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | ABL2 | P42684 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309599 | 0.90 | SMN1; SMN2 (0.42) | ITGB3ITGA2BHTR2BCPN1CPB2 | |
| SCHEMBL7310324 | 0.88 | HTR2B (0.40) | ITGB3ITGA2BHTR2B | |
| SCHEMBL7315337 | 0.87 | HTR2B (0.47) | ITGB3ITGA2BHTR2BPKMCPN1 | |
| SCHEMBL7307896 | 0.86 | HTR2B (0.46) | ITGB3ITGA2BHTR2BSIGMAR1OPRL1 | |
| SCHEMBL7304164 | 0.85 | ITGB3 (0.44) | ITGB3ITGA2BHTR2BPKMSIGMAR1 | |
| SCHEMBL7309068 | 0.84 | HTR2B (0.41) | ITGB3ITGA2BHTR2BPKMCHRM1 | |
| SCHEMBL7302525 | 0.83 | HTR2B (0.48) | ITGB3ITGA2BHTR2BSIGMAR1OPRL1 | |
| SCHEMBL7303264 | 0.83 | HTR2B (0.38) | ITGB3ITGA2BHTR2B | |
| SCHEMBL7313313 | 0.83 | HTR2B (0.45) | ITGB3ITGA2BHTR2BSIGMAR1OPRL1 | |
| SCHEMBL7306675 | 0.82 | ITGB3 (0.42) | ITGB3ITGA2BHTR2BPKMOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |